Morpholine → HCID 44218920, compound

HRID 1671547Notes

Reaction equation

HRID 1671547 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[NH2:13][C@H:14]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15]1.[NH:23]1[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1>>[C@H:14]1([NH:13][C:6]2[CH:5]=[CH:4][C:3]3[C:8](=[CH:9][CH:10]=[CH:11][C:2]=3[N:23]3[CH2:28][CH2:27][O:26][CH2:25][CH2:24]3)[N:7]=2)[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:16][CH2:15]1

Participants

4

Reactant 3

HCID 8083MorpholineHCID 2733933(R)-(-)-1-AminoindanHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 44218920HCID 44218920, compound

Procedure

The title compound, MS: m/e=346.4 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, (R)-1-aminoindane and morpholine.

Sources & evidence

ORD record
ord-26411311a9e745febece793738c6d477
Source dataset
uspto-grants-2011_08
Patent number
US07994324B2

Reaction notes

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