3-Thiophenamine, tetrahydro-, 1,1-dioxide → HCID 44218924, compound

HRID 1671548Notes

Reaction equation

HRID 1671548 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][O:14][C:15]1[CH:23]=[C:22]2[C:18]([CH2:19][CH2:20][CH:21]2[NH2:24])=[CH:17][CH:16]=1.[O:25]=[S:26]1(=[O:32])[CH2:30][CH2:29][CH:28]([NH2:31])[CH2:27]1>>[O:25]=[S:26]1(=[O:32])[CH2:30][CH2:29][CH:28]([NH:31][C:2]2[C:3]3[CH:4]=[CH:5][C:6]([NH:24][CH:21]4[C:22]5[C:18](=[CH:17][CH:16]=[C:15]([O:14][CH3:13])[CH:23]=5)[CH2:19][CH2:20]4)=[N:7][C:8]=3[CH:9]=[CH:10][CH:11]=2)[CH2:27]1

Participants

4

Reactant 3

HCID 228073-Thiophenamine, tetrahydro-, 1,1-dioxideHCID 99204636-Methoxy-1-IndanamineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 44218924HCID 44218924, compound

Procedure

The title compound, MS: m/e=424.3 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 6-methoxyindan-1-ylamine (CAS 103028-81-5) and 1,1-dioxido-tetrahydrothien-3-ylamine.

Sources & evidence

ORD record
ord-700269863bcc4c73ad529578a7d66aa6
Source dataset
uspto-grants-2011_08
Patent number
US07994324B2

Reaction notes

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