HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-Indan-1-yl-(5-nitro-quinolin-2-yl)-amine → (R)-N2-Indan-1-yl-quinoline-2,5-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-Indan-1-yl-(5-nitro-quinolin-2-yl)-amine | HCID 67096022 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (R)-N2-Indan-1-yl-quinoline-2,5-diamine | HCID 44219082 | — |
Reaction Steps
(R)-Indan-1-yl-(5-nitro-quinolin-2-yl)-amine (2.66 g, 8.7 mmol) was dissolved in 420 mL ethanol. Palladium on charcoal (10%, 463 mg, 0.4 mmol) was added and the reaction mixture war hydrogenated with a hydrogen balloon overnight. The palladium was filtered off and the solvent was evaporated. The title compound was obtained as a brown solid (2.29 g, 95%), MS: m/e=276.3 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07994324B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-9640605f56da41fca579637f2b8d52f3 |
| Source note | uspto-grants-2011_08 |