2-Chloro-5-nitroquinoline → n2-(7-Methoxy-indan-1-yl)-quinoline-2,5-diamine

HRID 1671555Notes

Reaction equation

HRID 1671555 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][O:16][C:17]1[CH:18]=[CH:19][CH:20]=[C:21]2[C:25]=1[CH:24]([NH2:26])[CH2:23][CH2:22]2>>[CH3:15][O:16][C:17]1[CH:18]=[CH:19][CH:20]=[C:21]2[C:25]=1[CH:24]([NH:26][C:8]1[CH:7]=[CH:6][C:5]3[C:4]([NH2:1])=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=1)[CH2:23][CH2:22]2

Participants

3

Reactant 2

HCID 3192512-Chloro-5-nitroquinolineHCID 186198817-Methoxy-2,3-dihydro-1H-inden-1-amine

Product 1

HCID 44219236n2-(7-Methoxy-indan-1-yl)-quinoline-2,5-diamine

Procedure

The title compound, MS: m/e=306.4 (M+H+), was prepared in accordance with the general method of example 16 from 5-nitro-2-chloroquinoline and 7-methoxy-indane-1-ylamine.

Sources & evidence

ORD record
ord-3768bc0ab5e94eecbebd9381d7234a95
Source dataset
uspto-grants-2011_08
Patent number
US07994324B2

Reaction notes

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