2-Chloro-5-nitroquinoline → HCID 44219552, compound

HRID 1671567Notes

Reaction equation

HRID 1671567 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[CH:21]([NH2:25])[CH2:20][CH2:19]2>>[F:15][C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[CH:21]([NH:25][C:8]1[CH:7]=[CH:6][C:5]3[C:4]([NH2:1])=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=1)[CH2:20][CH2:19]2

Participants

3

Reactant 2

HCID 3192512-Chloro-5-nitroquinolineHCID 166663285-Fluoro-2,3-dihydro-1H-inden-1-amine

Product 1

HCID 44219552HCID 44219552, compound

Procedure

The title compound, light yellow foam, MS: m/e=294.1 (M+H+), was prepared in accordance with the general method of example 16 from 5-nitro-2-chloroquinoline (example 16, CAS 13067-94-2) and commercially available (RS)-5-fluoro-indane-1-ylamine.

Sources & evidence

ORD record
ord-9882e5bc72214725a1448667ea0a0745
Source dataset
uspto-grants-2011_08
Patent number
US07994324B2

Reaction notes

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