反应详情

A mixture of the above described 4-methoxy-benzofuran-3-one oxime (6.15 g, 34.3 mmol) in EtOH (500 ml) with 10% Pd/C (6.15 g) was hydrogenated at 23° C. and atmospheric pressure for 18 h. Filtered the catalyst off, washed with EtOH, evaporated the filtrate totally and dried in high vacuum to give (RS)-4-methoxy-2,3-dihydro-benzofuran-3-ylamine as a light yellow oil (3.65 g, 64%); MS: m/e=166.2 (M+H|).

1. additionA mixture of the
2. customwas hydrogenated at 23° C.
3. filtrationFiltered the catalyst off,
4. washwashed with EtOH
5. customevaporated the filtrate totally
6. customdried in high vacuum