HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylbenzaldehyde → Methyl 3-chloro-2-oxo-3-(p-tolyl)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylbenzaldehyde | HCID 7725 | — |
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | Methyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoate | HCID 57437156 | — |
| Product | Methyl 3-chloro-2-oxo-3-(p-tolyl)propanoate | HCID 57437153 | — |
Reaction Steps
This compound was synthesised as 3-chloro-3-(4-fluoro-phenyl)-2-oxo-propionic acid methyl ester but using 4-methylbenzaldehyde instead 4-fluorobenzaldehyde. 1H-NMR (CDCl3): δ=2.35 (s, 3H); 3.83 (s, 3H); 6.13 (s, 1H); 7.21 (d, 2H); 7.28 (d, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07994336B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-3a150f16559f44d9b9355be5aebad987 |
| Source note | uspto-grants-2011_08 |