Nitric Acid → HCID 178526762, compound

Participants

Reaction Conditions

Reaction Steps

5 g (34 mmol) 4-hydroxyquinoline are added in small portions to nitric acid (66%) heated at 85° C. The reaction mixture is stirred for 50 min at this temperature. 150 ml water are heated to 100° C. and the reaction mixture is added slowly through a dropping funnel to the boiling water. The yellow precipitate which is formed is filtered off and washed with hot and cold water and acetone to become almost colorless. The title compound is dried at 60° C. under vacuum. mp: 357-358° C.; MS: 191 (M++1); HPLC: tret=8.73 min (Grad 3).

Provenance & Evidence