N-(2-Chlorophenyl)-6-methoxy-3-nitro-4-quinolinamine → HCID 60046938, compound

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Reaction Steps

The title compound is prepared in analogy to Example 19e, starting from 0.8 g (2.4 mmol) of (2-chloro-phenyl)-(6-methoxy-3-nitro-quinolin-4-yl)-amine (Example 44h) and 0.4 g Raney-Ni in 30 ml methanol. Time of hydrogenation: 1 h at rt. Crystallization of the product from ethyl acetate-hexane. mp: 120-123° C.; MS: 300 (M++1); HPLC: tret=8.41 min (Grad 1).

Provenance & Evidence