HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → 2-amino-5-ethylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | 5-ethyl-2,3-dihydro-1H-indole-2,3-dione | HCID 583487 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 2-amino-5-ethylbenzoic acid | HCID 7744486 | — |
Reaction Steps
The title compound is prepared by treating 24.7 g (0.141 mol) 5-ethyl-1H-indole-2,3-dione (Example 49a) with 40 ml of 30% H2O2 in 226 ml 5% sodium hydroxide solution following a procedure given by A. Baruffini et. al. in II Farmaco, Ed. Sc., 23, 3 (1968). mp: 128-129° C. (Lit.: 126° C.); MS: 166 (M++1); HPLC: tret=7.00 min (Grad 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07998972B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-60220c1b088d4472a0dbe7f836c61a2a |
| Source note | uspto-grants-2011_08 |