HCID 60046925, compound → HCID 60046928, compound

Participants

Reaction Steps

The title compound is prepared in analogy to Example 19e by hydrogenation at 0° C. for 86 min starting from 0.697 g (1.502 mmol) of (2-bromo-phenyl)-(3-nitro-6-phenyl-quinolin-4-yl)-amine (Example 53e) and 0.25 g Raney-Ni in 25 ml methanol-THF 2:1. Purification follows by chromatography on silica gel (ethyl acetate-hexane 1:1). mp: 174-177° C.; MS: 390 (M++1); HPLC: tret=10.50 min (Grad 1).

Provenance & Evidence