HCID 178510789, compound → HCID 10429677, compound

Participants

Reaction Steps

The title compound is prepared in analogy to Example 69 starting from 220 mg (0.559 mmol) N-hydroxy-2-[2-(8-phenyl-imidazo[4,5-c]quinolin-1-yl)-phenyl]-acetamidine (Example 68) and 120 mg Raney-Ni in 6 ml 0.5 N HCl at 50° C. for 9 h. The compound is purified by chromatography (THF-H2O-1N HCl 90:10:0.25) and precipitated from ethyl acetate. mp: 261-263° C.; MS: 378 (M++1); HPLC: tret=6.66 min (Grad 1).

Provenance & Evidence