2-Amino-5-methylbenzoic acid → HCID 67254551, compound

HRID 1672353Notes

Reaction equation

HRID 1672353 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([CH3:19])[CH:17]=2)[N:12]=[CH:11][C:10]=1[NH2:20].NC1C=CC(C)=CC=1[C:24](O)=[O:25]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:9]2[C:18]3[CH:17]=[C:16]([CH3:19])[CH:15]=[CH:14][C:13]=3[N:12]=[CH:11][C:10]=2[NH:20][C:24]1=[O:25]

Participants

3

Reactant 2

HCID 762552-Amino-5-methylbenzoic acidHCID 67333402HCID 67333402, compound

Product 1

HCID 67254551HCID 67254551, compound

Procedure

The title compound os obtained as described for Example 92 using N4-(2-chloro-phenyl)-6-methyl-quinoline-3,4-diamine, which is obtained as described for Example 92, steps a=to e) using 2-amino-5-methyl-benzoic acid (Fluka, Buchs, Switzerland) as starting material. Title compound: Analytical HPLC: tret=5.80 min (Grad. 2); ES-MS: m/e0=310.1, 312.1.

Workup

  1. customwhich is obtained

Sources & evidence

ORD record
ord-4e7d6a66a64149a1965f1332d7b6186b
Source dataset
uspto-grants-2011_08
Patent number
US07998972B2

Reaction notes

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