Potassium Carbonate → HCID 67330532, compound

Participants

Reaction Steps

To 7-(4-methoxy-phenyl)-isoquinoline-5-thiol sodium salt (0.29 g, 1 mmol) in acetone (10 mL), add (2-bromo-ethyl)-carbamic acid tert-butyl ester (0.22 g, 1 mmol) and potassium carbonate (0.14 g, 1 mmol). Stir the mixture at room temperature for 4 hr then load onto a silica gel column, and elute with 65% ethyl acetate in hexane to afford the title compound (0.35 g, 86%). Mass spectrum (LCMS) m/z=355.2 (M+H+).

Provenance & Evidence