HCID 24694245, compound → (3-Chloro-pyridin-2-ylsulfanyl)-acetic acid

HRID 1672405Notes

Reaction equation

HRID 1672405 reaction equation
ClC1C=CC(SCC(O)=O)=NC=1.C[O:14][C:15](=[O:25])[CH2:16][S:17][C:18]1[C:23]([Cl:24])=[CH:22][CH:21]=[CH:20][N:19]=1>>[Cl:24][C:23]1[C:18]([S:17][CH2:16][C:15]([OH:25])=[O:14])=[N:19][CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 24694245HCID 24694245, compoundHCID 47129949HCID 47129949, compound

Product 1

HCID 24711495(3-Chloro-pyridin-2-ylsulfanyl)-acetic acidYield 97%

Procedure

(3-Chloro-pyridin-2-ylsulfanyl)-acetic acid (19) was synthesized according to the procedure used for compound 15. Starting with 0.69 g (3.2 mmol) of corresponding ester 18 the target 19 was obtained as a white solid (0.63 g) in 97% yield.

Sources & evidence

ORD record
ord-503e6103bc144ef4b8a8cc11289841fc
Source dataset
uspto-grants-2011_08
Patent number
US07998980B2

Reaction notes

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