反应详情

A solution of 18.7 g (69.16 mmol) of [2-(5-phenylpentyloxy)phenyl]methanol from Example 27A in 120 ml of acetonitrile is mixed with 22.55 g (65.71 mmol) of triphenylphosphonium hydrobromide and heated to reflux for three hours. The reaction solution is then concentrated to dryness. 36.6 g (61.45 mmol, 83% yield) of crystalline product are obtained and are reacted without further purification.

1. temperatureheated
2. temperatureto reflux for three hours
3. concentrationThe reaction solution is then concentrated to dryness