Triphenylphosphine → HCID 86634292, compound

Participants

Reaction Steps

63.7 mg (0.24 mmol) of triphenylphosphine are dissolved in 2 ml of dichloromethane, 94 mg (0.24 mmol) of 5-fluoro-2-[3-(4-trifluoromethylphenyl)prop-2-ynyloxy]benzyl bromide, dissolved in 2 ml of dichloromethane, are added dropwise, and the mixture is stirred at room temperature overnight. The solvent is distilled out in vacuo, and the crystalline residue is stirred with petroleum ether. The resulting colorless crystals are filtered off with suction and dried on a clay dish. 109 mg (0.17 mmol, 69% of theory) of the title compound are obtained.

Provenance & Evidence