HCID 67352504, compound → HCID 67350133, compound

Participants

Reaction Steps

Compound 5 (0.496 g, 1.30 mmol) obtained in Example 5 was dissolved in ethanol/THF=5/1 (12 mL), and the mixture was stirred under a stream of hydrogen gas for 2 hours after adding 10% palladium-on-carbon (Pd—C) (50% water, 276 mg, 0.130 mmol). Insolubles were separated by filtration through sellite, and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography to give the title compound (Compound 6) (0.410 g, 90%).

Provenance & Evidence