Hydrogen chloride-ethyl acetate → HCID 67352345, compound

Participants

Reaction Conditions

Reaction Steps

Compound 23 (1.99 g, 4.48 mmol) obtained in Example 23 was dissolved in ethyl acetate (20 mL), and the mixture was stirred at 60° C. for 4 hours after adding 4 mol/L hydrogen chloride-ethyl acetate (20 mL) at room temperature. Back at room temperature, the reaction mixture was concentrated under reduced pressure, ethyl acetate (50 mL) was added to the resulting residue, and the mixture was stirred overnight at room temperature. The precipitated solid was filtered off, and dried to give the title compound (Compound 24) (1.72 g, 92%) as a yellow solid.

Provenance & Evidence