Lawesson's reagent → HCID 86643700, compound

Participants

Reaction Steps

3-(3-Iodophenyl)-4-methyl-1,2,4-oxadiazol-5(4H)-one (400 mg, 1.32 mmol) obtained in Step 2 was dissolved in toluene (10 mL), and the mixture was heated to reflux for 7 days after adding Lawesson's reagent (801 mg, 1.98 mmol). The mixture was then purified by silica gel column chromatography to give 3-(3-iodophenyl)-4-methyl-1,2,4-oxadiazole-5(4H)-thione (401 mg, 95%).

Provenance & Evidence