Saccharin → HCID 86630495, compound

Participants

Reaction Conditions

Reaction Steps

Two-necked 25 ml RB flask was charged with PdCl2 (0.177 g, 1 mmol), LiCl (0.100 g, 2.4 m mol) and MeOH (2 ml). The resulting reaction mixture was stirred under argon atmosphere at 25° C. for 2.5 h. Then to the same reaction was added NaOAc (0.123 g, 1.5 mmol), and a solution of saccharin (formula 7) (0.183 g, 1 mmol) in MeOH (2 ml). The resulting reaction mixture was stirred at 25° C. for 72 h. Then distilled water (6 ml) was added to it and the solid was filtered on sintered funnel, washed with water and dried under reduced pressure (5 mm) for 3 h to afford palladium complex (formula 8) where in R═H and R1=Me as brown colored solid. Yield: 75%, mp: 240° C. (decomp.)

Provenance & Evidence