Dicyclohexylcarbamoyl chloride → 1,1-Bis-(cyclohexyl)-5-(2,2,2-trifluoroethyl) biuret
Reaction equation
[CH:1]1([N:7]([CH:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[C:8](Cl)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[F:17][C:18]([F:25])([F:24])[CH2:19][NH:20][C:21]([NH2:23])=[O:22]>>[CH:1]1([N:7]([CH:11]2[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]2)[C:8]([NH:23][C:21]([NH:20][CH2:19][C:18]([F:25])([F:24])[F:17])=[O:22])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1Participants
3
Procedure
Prepared as described in General Procedure 1 using dicyclohexyl carbamoyl chloride and N-2,2,2-trifluoroethylurea.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-6be1345ed97e4067befc5d179fac0b41
- Source dataset
- uspto-grants-2011_08
- Patent number
- US07999114B2
Reaction notes
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