Acetic Acid → 2-Chloro-5-[3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1(2H)-pyrimidinyl]benzaldehyde

HRID 167317Notes

Reaction equation

HRID 167317 reaction equation
[CH3:27][C:28](=[O:29])[OH:30].[Cl:2][c:3]1[c:4]([CH:22]2[O:23][CH2:26][CH2:25][O:24]2)[cH:5][c:6](-[n:9]2[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[cH:7][cH:8]1.[OH2:1]>>[Cl:2][c:3]1[c:4]([CH:22]=[O:23])[cH:5][c:6](-[n:9]2[c:10](=[O:21])[n:11]([CH3:20])[c:12]([C:16]([F:17])([F:18])[F:19])[cH:13][c:14]2=[O:15])[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 962WaterHCID 212012713-(4-Chloro-3-(1,3-dioxolan-2-yl)-phenyl)-2,4-dioxo-1-methyl-6-trifluoromethyl-1,2,3,4-tetrahydropyrimidine

Product 1

HCID 212012252-Chloro-5-[3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1(2H)-pyrimidinyl]benzaldehyde

Sources & evidence

ORD record
ord-ec10061cfaa54916b64eb20ef512fc2d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…