Methanol → Tert-butyl 2-amino-4-phenethylbenzoate

Participants

Reaction Steps

0.74 g of 5% palladium-carbon was added to a mixed solution of 56 mL of methanol and 56 mL of ethyl acetate containing 3.7 g of tert-butyl 2-nitro-4-((E)-2-phenylvinyl)benzoate and stirred under hydrogen atmosphere at room temperature for 2 hours. Insoluble were removed by filtration, and the solvent was evaporated under reduced pressure to obtain 3.4 g of tert-butyl 2-amino-4-phenethylbenzoate as white solid.

Provenance & Evidence