HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1673352Generated: October 31, 2026
Hydrochloric Acid → Methyl 2-(benzamido)-4-hydroxybenzoate
https://huagongshe.com/reaction/1673352
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | Methyl 2-(benzamido)-4-methoxybenzoate | HCID 57879519 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 2-(benzamido)-4-hydroxybenzoate | HCID 57879368 | 36.1% |
Reaction Steps
0.94 g of aluminum chloride was added to 7 mL of toluene solution containing 0.67 g of methyl 2-(benzamido)-4-methoxybenzoate at room temperature and stirred at 80° C. for 2 hours and 30 minutes. After the reaction mixture was cooled to room temperature, ethyl acetate and 1.0 mol/L hydrochloric acid were added and a solid substance was separated by filtration to obtain 0.23 g of methyl 2-(benzamido)-4-hydroxybenzoate as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07999132B2 |
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| Source dataset | uspto-grants-2011_08 |
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| ORD ID | ord-512d32b75cf64791a1c5d1d76626eb2c |
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| Source note | uspto-grants-2011_08 |
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