Hydrochloric Acid → HCID 57879622, compound

Participants

Reaction Steps

0.4 mL of 10% aqueous sodium hydroxide was added to 6 ml of ethanol suspension containing 0.30 g of methyl 2-(benzamido)-4-(phenylthio)benzoate at room temperature, and the resulting mixture was heated to reflux for 1 hour. After one reaction mixture was cooled to room temperature, 1.0 mol/b hydrochloric acid and ethyl acetate were added. The organic layer was separated and dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure. Diisopropyl ether and hexane were added to the obtained residue and a solid substance was separated, by filtration to obtain 0.28 g of 2-(benzamido)-4-(phenylthio)benzoic acid as white solid.

Provenance & Evidence