Tert-butyl 4-(2,4-difluorophenyl)-2-(4-fluorobenzamido)benzoate → 4-(2,4-Difluorophenyl)-2-(4-fluorobenzamido)benzoic acid

Participants

Reaction Steps

10 mL of trifluoroacetic acid was added to the obtained tert-butyl 4-(2,4-difluorophenyl)-2-(4-fluorobenzamido)benzoate and stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure and diisopropyl ether was added to the obtained residue and a solid substance was separated by filtration to obtain 46 mg of 4-(2,4-difluorophenyl)-2-(4-fluorobenzamido)benzoic acid as white solid.

Provenance & Evidence