HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(benzo[1,3]dioxol-5-yl)-2-(4-fluorobenzamido)benzoate → 4-(Benzo[1,3]dioxol-5-yl)-2-(4-fluorobenzamido)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(benzo[1,3]dioxol-5-yl)-2-(4-fluorobenzamido)benzoate | HCID 67344518 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 4-(Benzo[1,3]dioxol-5-yl)-2-(4-fluorobenzamido)benzoic acid | HCID 57879591 | — |
Reaction Steps
10 mL of trifluoroacetic acid was added to the obtained tert-butyl 4-(benzo[1,3]dioxol-5-yl)-2-(4-fluorobenzamido)benzoate and stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure and diisopropyl ether was added to the obtained residue and a solid substance was separated by filtration to obtain 39 mg of 4-(benzo[1,3]dioxol-5-yl)-2-(4-fluorobenzamido)benzoic acid as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07999132B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-9efd75568c7d4431a475753ac63b0f5a |
| Source note | uspto-grants-2011_08 |