HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 2-(2,3-dimethylbenzamido)-4-(4-(tert-butoxycarbonyl)oxyphenyl)benzoate → 2-(2,3-Dimethylbenzamido)-4-(4-hydroxyphenyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 2-(2,3-dimethylbenzamido)-4-(4-(tert-butoxycarbonyl)oxyphenyl)benzoate | HCID 67342726 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 2-(2,3-Dimethylbenzamido)-4-(4-hydroxyphenyl)benzoic acid | HCID 57879479 | — |
Reaction Steps
10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(2,3-dimethylbenzamido)-4-(4-(tert-butoxycarbonyl)oxyphenyl)benzoate and stirred ah room temperature for 2 hours. The solvent was evaporated under reduced pressure and ethyl acetate was added to the obtained residue and a solid substance was separated by filtration to obtain 20 mg of 2-(2,3-dimethylbenzamido)-4-(4-hydroxyphenyl)benzoic acid as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07999132B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-a30d5ffaa6034487adc5abfb425a26eb |
| Source note | uspto-grants-2011_08 |