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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1673459Generated: October 30, 2026

Tert-butyl 2-(benzamido)-4-(3-chlorophenyl)benzoate → 2-(Benzamido)-4-(3-chlorophenyl)benzoic acid

https://huagongshe.com/reaction/1673459

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 2-(benzamido)-4-(3-chlorophenyl)benzoateHCID 67344272—
SolventTrifluoroacetic acidHCID 6422—
Product2-(Benzamido)-4-(3-chlorophenyl)benzoic acidHCID 57879379—

Reaction Steps

10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(benzamido)-4-(3-chlorophenyl)benzoate and stirred at room temperature for 1 hour. The solvent was evaporated under reduced pressure and methanol was added to the obtained residue and a solid substance was separated by filtration to obtain 21 mg of 2-(benzamido)-4-(3-chlorophenyl)benzoic acid as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07999132B2
Source datasetuspto-grants-2011_08
ORD IDord-e92718cd844f461a989355a4478175e1
Source noteuspto-grants-2011_08