Tert-butyl 2-(benzamido)-4-(2-fluorophenyl)benzoate → 2-(Benzamido)-4-(2-fluorophenyl)benzoic acid

Participants

Reaction Steps

10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(benzamido)-4-(2-fluorophenyl)benzoate and stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure and toluene was added. The solvent was evaporated under reduced pressure and diisopropyl ether was added to the obtained residue and a solid substance was separated by filtration to obtain 93 mg of 2-(benzamido)-4-(2-fluorophenyl)benzoic acid as white solid.

Provenance & Evidence