Methanol → HCID 57879348, compound

Participants

Reaction Steps

1.3 mg of 10% palladium-carbon was added to a mixed solution of 1.0 mL of methanol and 1.0 mL of ethyl acetate containing 10 mg of 4-phenoxy-2-((E)-4-phenyl-3-butenamido)benzoic acid and stirred under hydrogen atmosphere at room temperature for 6 hours. After insoluble were removed by filtration, the solvent was evaporated under reduced pressure. Hexane and diisopropyl ether were added to the obtained residue and a solid substance was separated by filtration to obtain 4.6 mg of 4-phenoxy-2-(4-phenylbutanamido)benzoic acid as white solid.

Provenance & Evidence