Trifluoroacetic acid → HCID 57879476, compound

Participants

Reaction Steps

1.0 mL of trifluoroacetic acid was added to 1.0 mL of methylene chloride solution containing 20 mg of tert-butyl 4-phenyl-2-(3-(1H-tetrazol-1-yl)benzamido)benzoate and stirred an room temperature for 1 hour. The solvent was evaporated under reduced pressure and ethyl acetate and tetrahydrofuran were added to the obtained residue and headed to 50° C., Insoluble were removed by filtration at the same temperature, and the solvent was evaporated under reduced pressure. Tetrahydrofuran was added to the obtained residue and a solid substance was separated by filtration to obtain 5.0 mg of 4-phenyl-2-(3-(1H-tetrazol-1-yl)benzamido)benzoic acid as white solid.

Provenance & Evidence