4,6-Dichloropyrimidine → HCID 66991795, compound

HRID 1674511Notes

Reaction equation

HRID 1674511 reaction equation
Cl[C:2]1[CH:7]=[C:6](Cl)[N:5]=[CH:4][N:3]=1.[NH2:9][C:10]1[C:11]([CH3:17])=[C:12]([OH:16])[CH:13]=[CH:14][CH:15]=1>>[OH:16][C:12]1[C:11]([CH3:17])=[C:10]([NH:9][C:2]2[CH:7]=[C:6]([NH:9][C:10]3[CH:15]=[CH:14][CH:13]=[C:12]([OH:16])[C:11]=3[CH3:17])[N:5]=[CH:4][N:3]=2)[CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 709434,6-DichloropyrimidineHCID 1044482-Amino-o-cresol

Product 1

HCID 66991795HCID 66991795, compoundYield 40%

Procedure

This compound was obtained (yield 40%) based on the method described in Production Example 2B using 4,6-dichloropyrimidine instead of the 4,6-dichloro-2-ethylpyrimidine, and using 3-amino-2-methylphenol instead of the 3-aminophenol.

Workup

  1. customThis compound was obtained (yield 40%)

Sources & evidence

ORD record
ord-cb517cf88bc54935ba4e25b3427af935
Source dataset
uspto-grants-2011_08
Patent number
US08003645B2

Reaction notes

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