反应详情

A solution of (3-amino-4-chloro-phenyl)-methanol (2.0 g, 12.7 mmol) in pyridine (26 mL) was treated with 3,4-dimethoxybenzenesulfonyl chloride (3.3 g, 1.1 eq). The solution was stirred at RT overnight. The mixture was then partitioned between EA and 3M HCl. The organic layer was washed with brine, dried over MgSO4 and concentrated. The product was recovered as a brownish foam.

1. customThe mixture was then partitioned between EA and 3M HCl
2. washThe organic layer was washed with brine
3. dry with materialdried over MgSO4
4. concentrationconcentrated
5. customThe product was recovered as a brownish foam