HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → Ethyl[(pyrimidin-5-yl)methyl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | 5-(Chloromethyl)pyrimidine | HCID 14720296 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Ethyl[(pyrimidin-5-yl)methyl]amine | HCID 57419853 | — |
Reaction Steps
prepared by reaction of the 5-chloromethyl-pyrimidine (Russell M. G. N et al J. Med. Chem. 2005, 48, 5, 1367-1383) with 2M ethylamine in THF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003654B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-eb39361f00d64d1b91b8dcb4ffd582e1 |
| Source note | uspto-grants-2011_08 |