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HRID1675012

反应详情

EQUATION

反应方程式

HRID 1675012 的结构方程式

REACTANTS

反应物

2
结构：N#Cc1cccc(Br)c1
HCID23381

Benzonitrile, m-bromo-

C7H4BrN

结构：O=C1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1
HCID59578369

未命名化合物

PRODUCTS

生成物

1
结构：N#Cc1cccc(C2(O)CCN(c3ccc4nnc(C(F)(F)F)n4n3)CC2)c1
HCID59149737

未命名化合物

收率 26%

PROCEDURE

实验过程

A mixture of 1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-one and 3-bromobenzonitrile was allowed to react by the method of Example 315 to give 3-[4-hydroxy-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]benzonitrile in 26% yield.

WORKUP

后处理

  1. customto react by the method of Example 315