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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675014Generated: October 29, 2026

4-(4-Fluorophenyl)piperidin-4-ol → HCID 44125832, compound

https://huagongshe.com/reaction/1675014

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Fluorophenyl)piperidin-4-olHCID 77497—
Reactant6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazineHCID 613657—
ProductHCID 44125832HCID 4412583274%

Reaction Steps

A mixture of 4-(4-fluorophenyl)piperidin-4-ol and 6-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by the method of Example 306 to give 4-(4-fluorophenyl)-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-ol in 74% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-39b732b1a21b419cb037004948cf5ec8
Source noteuspto-grants-2011_08