Benzyl 4-oxopiperidine-1-carboxylate → HCID 67340593, compound

HRID 1675022Notes

Reaction equation

HRID 1675022 reaction equation
[O:1]=[C:2]1[CH2:7][CH2:6][N:5]([C:8]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:9])[CH2:4][CH2:3]1.Br[C:19]1[CH:24]=[C:23]([CH3:25])[CH:22]=[CH:21][N:20]=1>>[OH:1][C:2]1([C:19]2[CH:24]=[C:23]([CH3:25])[CH:22]=[CH:21][N:20]=2)[CH2:3][CH2:4][N:5]([C:8]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[O:9])[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 643496Benzyl 4-oxopiperidine-1-carboxylateHCID 27340872-Bromo-4-methylpyridine

Product 1

HCID 67340593HCID 67340593, compoundYield 56%

Procedure

Obtained in 56% yield by an analogous method to Example 321, preparation of starting materials, starting from benzyl 4-oxo-1-piperidinecarboxylate and 2-bromo-4-methylpyridine.

Workup

  1. customObtained in 56% yield by an analogous method to Example 321, preparation of starting materials

Sources & evidence

ORD record
ord-c17aa56b61314d489b21dd105ede838d
Source dataset
uspto-grants-2011_08
Patent number
US08003649B2

Reaction notes

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