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HRID1675023

反应详情

EQUATION

反应方程式

HRID 1675023 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1nnc2ccc(Cl)nn12
HCID613657

6-chloro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine

C6H2ClF3N4

结构：OC1(c2ccc(Cl)nc2)CCNCC1
HCID21105533

未命名化合物

PRODUCTS

生成物

1
结构：OC1(c2ccc(Cl)nc2)CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1
HCID59149692

未命名化合物

收率 80%

PROCEDURE

实验过程

A mixture of 4-(6-chloropyridin-3-yl)piperidin-4-ol and 6-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by the method of Example 306 to give 4-(6-chloropyridin-3-yl)-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-ol in 80% yield.

WORKUP

后处理

  1. customto react by the method of Example 306