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HRID1675040

反应详情

EQUATION

反应方程式

HRID 1675040 的结构方程式

REACTANTS

反应物

2
结构：Cc1cccc(C)c1N1CCNCC1
HCID70538

1-(2,6-Xylyl)piperazine

C12H18N2

结构：FC(F)(Cl)c1nnc2ccc(Cl)nn12
HCID1489114

6-chloro-3-[chloro(difluoro)methyl]-[1,2,4]triazolo[4,3-b]pyridazine

C6H2Cl2F2N4

PRODUCTS

生成物

1
结构：Cc1cccc(C)c1N1CCN(c2ccc3nnc(C(F)(F)Cl)n3n2)CC1
HCID59149771

未命名化合物

收率 64%

PROCEDURE

实验过程

A mixture of 1-(2,6-dimethylphenyl)piperazine and 6-chloro-3-[chloro(difluoro)methyl]-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by an analogous method to Example 339 to give 3-[chloro(difluoro)methyl]-6-[4-(2,6-dimethylphenyl)piperazin-1-yl][1,2,4]triazolo[4,3-b]pyridazine in 64% yield.

WORKUP

后处理

  1. customto react by an analogous method to Example 339