Dimethylamine → HCID 11613210, compound

HRID 1675209Notes

Reaction equation

Cl[CH2:2][C:3]([NH:5][CH2:6][CH2:7][C:8]([NH:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][N:15]=[C:14]2[NH:21][C:22]1[CH:27]=[CH:26][C:25]([O:28][C:29]2[CH:30]=[N:31][C:32]([CH3:35])=[CH:33][CH:34]=2)=[C:24]([CH3:36])[CH:23]=1)=[O:9])=[O:4].[CH3:37][NH:38][CH3:39]>>[CH3:37][N:38]([CH3:39])[CH2:2][C:3]([NH:5][CH2:6][CH2:7][C:8]([NH:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][N:15]=[C:14]2[NH:21][C:22]1[CH:27]=[CH:26][C:25]([O:28][C:29]2[CH:30]=[N:31][C:32]([CH3:35])=[CH:33][CH:34]=2)=[C:24]([CH3:36])[CH:23]=1)=[O:9])=[O:4]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 11555204HCID 11555204, compound

Product 1

HCID 11613210HCID 11613210, compoundYield 50%

Procedure

The procedure of Example 62 was repeated except for using 0.08 g of the compound obtained in Example 67 and 0.24 ml of dimethylamine 2 M THF instead of the compound obtained in Example 61 to obtain the title compound (0.04 g, 50%).

Sources & evidence

ORD record: ord-8759dc45fa2b40c18d63004d17c704cc
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08003658B2

Reaction notes

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