HCID 11526570, compound → HCID 67333750, compound

HRID 1675222Notes

Reaction equation

HRID 1675222 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][C:5]([NH:7]C1C=C2C(=CC=1)N=CN=C2NC1C=CC(OCC2C=CC=C(F)C=2)=C(Cl)C=1)=[O:6].C(OC(=O)NCCCC([C:47]1[CH:48]=[C:49]2[C:54](=[CH:55][CH:56]=1)[N:53]=[CH:52][N:51]=[C:50]2[NH:57][C:58]1[CH:63]=[CH:62][C:61]([O:64][C:65]2[CH:66]=[N:67][C:68]([CH3:71])=[CH:69][CH:70]=2)=[C:60]([CH3:72])[CH:59]=1)=O)(C)(C)C>>[NH2:1][CH2:2][CH2:3][CH2:4][C:5]([NH:7][C:47]1[CH:48]=[C:49]2[C:54](=[CH:55][CH:56]=1)[N:53]=[CH:52][N:51]=[C:50]2[NH:57][C:58]1[CH:63]=[CH:62][C:61]([O:64][C:65]2[CH:66]=[N:67][C:68]([CH3:71])=[CH:69][CH:70]=2)=[C:60]([CH3:72])[CH:59]=1)=[O:6]

Participants

3

Reactant 2

HCID 11526570HCID 11526570, compoundHCID 67335089HCID 67335089, compound

Product 1

HCID 67333750HCID 67333750, compoundYield 98%

Procedure

The procedure of (87-1) of Example 87 was repeated except for using 1.51 g of the compound obtained in Example 99 instead of the compound obtained in example 86 to obtain the title compound (1.21 g, 98%).

Sources & evidence

ORD record
ord-3708046db3a446bfb2bfefc09ce01133
Source dataset
uspto-grants-2011_08
Patent number
US08003658B2

Reaction notes

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