Chloroform → HCID 67334034, compound

Participants

Reaction Conditions

Reaction Steps

0.32 ml of ammonia water was added to 130 mg of the compound obtained in Example 148 diluted with 10 ml of methanol, and the solution was refluxed with stirring at 80° C. for 26 hours. The reacted solution was cooled to room temperature, and filtered under a reduced pressure to obtain solid. The solid was subjected to column chromatography (eluent-chloroform:methanol=15:1) to obtain the title compound (80 mg, 66%).

Provenance & Evidence