反应详情

温度

0 °C

To a solution of 62.3 (0.61 g, 3.58 mmol) and pyridine (0.29 mL, 3.58 mmol) in DCM (24 mL) was added bromine (3.58 mL, 1.0 M solution in DCM) dropwise at 0° C. The mixture was stirred for 30 minutes at 0° C. and warmed to room temperature over 1 Hour. Upon completion, the reaction was diluted with DCM, washed with saturated Na2S2O3 and brine, dried (Na2SO4), and concentrated to afford 62.4. The crude product was used without further purification.

1. temperaturewarmed to room temperature over 1 Hour
2. washwashed with saturated Na2S2O3 and brine
3. dry with materialdried (Na2SO4)
4. concentrationconcentrated