HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phenethylamine → N-Phenethyl-6-[5-(2-trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrole-2-yl]nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phenethylamine | HCID 1001 | — |
| Edukt | 6-[5-(2-Trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-2-yl]nicotinic acid | HCID 58459784 | — |
| Produkt | N-Phenethyl-6-[5-(2-trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrole-2-yl]nicotinamide | HCID 25105829 | 45% |
Reaktionsschritte
6-[5-(2-Trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-2-yl]nicotinic acid (50 mg, 0.124 mmol) was reacted with 2-phenylethylamine analogously to example 3d. Yield: 45%, M+H+: 507.28.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08003677B2 |
| Quelldatensatz | uspto-grants-2011_08 |
| ORD ID | ord-4ea7b83396f84557a670deac8a405814 |
| Quellennotiz | uspto-grants-2011_08 |