2-Cyclopentylethanamine → HCID 59360915, compound

HRID 1675366Notes

Reaction equation

HRID 1675366 reaction equation
[F:1][C:2]([F:29])([F:28])[C:3]1[CH:27]=[CH:26][CH:25]=[CH:24][C:4]=1[C:5]([N:7]1[CH2:11][C:10]2[CH2:12][N:13]([C:15]3[CH:23]=[CH:22][C:18]([C:19]([OH:21])=O)=[CH:17][N:16]=3)[CH2:14][C:9]=2[CH2:8]1)=[O:6].[CH:30]1([CH2:35][CH2:36][NH2:37])[CH2:34][CH2:33][CH2:32][CH2:31]1>>[CH:30]1([CH2:35][CH2:36][NH:37][C:19](=[O:21])[C:18]2[CH:22]=[CH:23][C:15]([N:13]3[CH2:14][C:9]4[CH2:8][N:7]([C:5](=[O:6])[C:4]5[CH:24]=[CH:25][CH:26]=[CH:27][C:3]=5[C:2]([F:29])([F:1])[F:28])[CH2:11][C:10]=4[CH2:12]3)=[N:16][CH:17]=2)[CH2:34][CH2:33][CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 53056502-CyclopentylethanamineHCID 584597846-[5-(2-Trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-2-yl]nicotinic acid

Product 1

HCID 59360915HCID 59360915, compoundYield 34%

Procedure

6-[5-(2-Trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-2-yl]nicotinic acid (50 mg, 0.124 mmol) was reacted with cyclopentylethylamine analogously to example 3d. Yield: 34%, M+H+: 499.28.

Sources & evidence

ORD record
ord-3c49cf25308149beb58a56abf2376967
Source dataset
uspto-grants-2011_08
Patent number
US08003677B2

Reaction notes

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