HRID1675411

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID18673010

4-(Trifluoromethyl)-1,3-thiazole-2-carboxylic acid

C5H2F3NO2S

结构：COc1ccc(C(C)=O)c(NC(=O)c2nc(C(C)C)cs2)c1

HCID20773655

N-(2-Acetyl-5-methoxyphenyl)-4-(1-methylethyl)-2-thiazolecarboxamide

C16H18N2O3S

HCID25067316

1-(2-Amino-4-methoxy-3-methylphenyl)ethan-1-one

C10H13NO2

PRODUCTS

生成物

结构：COc1ccc(C(C)=O)c(NC(=O)c2nc(C(F)(F)F)cs2)c1C

HCID56605151

N-(6-Acetyl-3-methoxy-2-methylphenyl)-4-(trifluoromethyl)-1,3-thiazole-2-carboxamide

C15H13F3N2O3S

收率 74%

PROCEDURE

实验过程

Compound 64b was synthesized from 4-(trifluoromethyl)-1,3-thiazole-2-carboxylic acid and 1-(2-amino-4-methoxy-3-methylphenyl)-ethanone as a beige solid in 74% yield, following the procedure as described for compound 42a.