HRID1675439

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID57578732

未命名化合物

结构：C=CCCCCN(C)C(=O)[C@@H]1C[C@H](Oc2cc(-n3ccc(C(F)(F)F)n3)nc3c(Cl)c(OC)ccc23)CN1C(=O)OC(C)(C)C

HCID57816700

未命名化合物

PRODUCTS

生成物

结构：C=CCCCCN(C)C(=O)[C@@H]1C[C@H](Oc2cc(-n3ccc(C(F)(F)F)n3)nc3c(Cl)c(OC)ccc23)CN1

HCID57816693

未命名化合物

PROCEDURE

实验过程

Compound 115 was synthesized from compound 114 as a white solid in quantitative yield, following the procedure as described for compound 82.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0c96fe7ef97f48a9817eeb5b636f4438
来源数据集: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08003659B2
来源说明: uspto-grants-2011_08

反应 SMILES

[Cl:1][C:2]1[C:3]([O:44][CH3:45])=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([N:12]1[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[N:13]1)[CH:8]=[C:7]2[O:21][C@@H:22]1[CH2:26][N:25](C(OC(C)(C)C)=O)[C@H:24]([C:34](=[O:43])[N:35]([CH2:37][CH2:38][CH2:39][CH2:40][CH:41]=[CH2:42])[CH3:36])[CH2:23]1.C(C1(S(N)(=O)=O)CC1)#C>>[Cl:1][C:2]1[C:3]([O:44][CH3:45])=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([N:12]1[CH:16]=[CH:15][C:14]([C:17]([F:18])([F:19])[F:20])=[N:13]1)[CH:8]=[C:7]2[O:21][C@@H:22]1[CH2:26][NH:25][C@H:24]([C:34]([N:35]([CH2:37][CH2:38][CH2:39][CH2:40][CH:41]=[CH2:42])[CH3:36])=[O:43])[CH2:23]1