Hydrochloric Acid → HCID 57445721, compound

Participants

Reaction Steps

To 50 ml of ethanol were added 10.8 g of 2-propynyl 4-(2-propynyloxy)-3-fluorobenzoate and 30 ml of a 15% aqueous sodium hydroxide solution, and the resulting mixture was stirred at room temperature for 2 hours. Thereafter, the reaction mixture was added to hydrochloric acid to make the mixture acidic. The precipitated crystals were collected by filtration and dried, and 8.0 g of 4-(2-propynyloxy)-3-fluorobenzoic acid was obtained.

Provenance & Evidence